Learning outcomes of the curricular unit (knowledge, skills and competences to be developed by the students)
Ability to acquire and understand knowledge about the pathophysiological processes of the organism as a whole, integrating the aspects of human physiology Ability to acquire and understand knowledge about the epidemiological method and its application in the analysis of health problems, identifying the fundamental differences of the same regarding the clinical method Ability to acquire and understand knowledge regarding the use of drugs, according to the pharmacokinetic, pharmacodynamics and mechanism of action, taking into account the circumstances of the person that may affect the therapeutic response to them Development of critical capacity in the evaluation and response to health problems, articulating the individual and collective dimensions, aiming at the rational use of therapeutic resources.
Syllabus
Cell injury The inflammatory process Immune response Hemodynamic disorders Neoplasms Environmental pathology General concepts about genetic diseases Concept and emergence of epidemiology Epidemiological method vs clinical method: differentiating criteria Epidemiological Lexicon: basic concepts Epidemiological studies Epidemiological surveillance and epidemiological surveillance systems General notions of therapy Notions of pharmacodynamics and pharmacokinetics Variations in response to administration of drugs Interactions and drug toxicity Pharmacology, special populations: children, the elderly and pregnant women Technical and socio-economic aspects of therapeutics Regulation of medicines in Portugal and the European Union-EMA and FDA
Demonstration of the syllabus coherence with the curricular unit's learning objectives
The contents of the curricular unit allow students to acquire knowledge about the functioning of the human body in the pathophysiological dimension, based on human physiology. Clinical and epidemiological methods form the basis of reasoning in the analysis of health problems at individual and collective levels, respectively, which is of particular importance in the construction of care planning capacity, taking into account characteristics and phenomena that enhance epidemiological transition. The knowledge of the drugs and the human response to them allows to articulate the evaluation of the physio pathological dimension with adequate therapeutic responses. The political and socioeconomic dimension of drugs contributes to the construction of a critical and reflective professional conscience, promoting rationality in the use of drugs.
Teaching methodologies (including evaluation)
Expository sessions, guided study and analysis of group situations. The evaluation will be based on two written tests (50% each). The autonomous component of the curricular unit must be carried out by the student through: analysis of the scientific bibliography on the topics addressed and others considered complementary.
Demonstration of the coherence between the teaching methodologies and the learning outcomes
Being the basic contents for the understanding of the health-disease process, at the individual and collective levels, the expository method seems appropriate, in the first moment of approaching them. The bibliographical research and oriented study constitute fundamental methodologies, in continuity and as support of the previous, by the contribution of information that allows. The analysis of situations in groups allows students to develop critical and reflective capacity by confronting ideas and integrating the various content areas addressed in the curricular unit. It also allows the development of a position of responsibility in the knowledge, understanding and good use of community resources.
Bibliography (Mandatory resources)
Bonita, R., et al (2010). Epidemiologia básica (2ª ed.). OMS. Lei n.º 81/2009 de 21 de Agosto - Sistema de Vigilância em Saúde Pública. Despacho Nº 5855/2014, de 5 de maio. Diário da República nº 85/15 - II Série. SINAVE. Ritter, J., et al. (2019). Rang & Dale's Pharmacology. (9th ed.). Elsevier Health Sciences. Brunton, L., et al. (2017). Goodman & Gilman's: The Pharmacological Basis of Therapeutics. (13th ed.). McGraw Hill. Machado RM, et al. (2020).The vaginal sheet: an innovative form of vaginal film for the treatment of vaginal infections. Drug Development and Industrial Pharmacy. Machado RM, et al. (2019) Optimization and Application of In Vitro and Ex Vivo Models for Vaginal Semisolids Safety Evaluation. Journal of Pharmaceutical Sciences. Kumar, V., et al. (2020). Robbins Essential Pathology. (1st ed.). Elsevier Health Sciences. Norris, T. (2019). Port's Essentials of Patophysiology. (5th ed.). Wolters Kluwer Health.
