| Code: | LBBA1151 | Acronym: | BIOQ1 | |
| Scientific Area: | Biology and Biochemistry | |||
| Teaching Area: | Ciências Químicas e Físicas (CQF) |
| Acronym | Nº de Estudantes | Plano de Estudos | Academic Year | Credits | Horas Contacto | Total Hours |
|---|---|---|---|---|---|---|
| LBBA | 13 | Despacho n.º 7512/2022 de 15/06 | 1º | 5 | 60 | 140 |
| Ensino Teórico: | 30,00 |
| Ensino Prático e Laboratorial: | 20,00 |
Teaching - Weekly Hours
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Teaching - Responsabilities
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Knowledge of organic chemistry, structure and function of biomolecules. Study of the properties of biomolecules and development of practical skills in biochemical methods. Development of the capacity for data analysis, synthesis and scientific writing. Development of teamwork, of self-learning and autonomous work.
Theoretical: 1.Aspects of organic chemistry important in biochemistry: funcional groups, polarity and types of reactions. 2. Nomenclature of organic compounds. 3. Optic isomerism and biological activity. 4. Water and hydrogen bonds. 5. Aminoacids: structure, classification and chemical reactions. 6. Proteins: structural levels, classification, denaturation, solubility. 7. Carbohydrates: structure, classification and properties. 8. Lípids: structure and classification. 9. Enzymes: models of enzimatic action, cinetics and regulation. 10. Enzymes in biotechnology. 11. Biopolymers. Laboratorial: 1.Buffers. 2. Sample Preparation. 3. Spectroscopic methods for assay of proteins and carbohydrates. 4. Enzymatic Catalysis.
The contents are organized over the fundamental role of biochemistry in the study of life sciences and its use in biotechnology. The curricular unit starts by providing the concepts of organic chemistry that will be necessary for the full comprehension of biomolecules¿ properties. It will proceed to the in-depth knowledge of each biomolecule, with an emphasis on enzymes and its utilization in biotechnology, and ending with biopolymers. Laboratory classes will promote the integration of the theorical concepts and allow the development of practical skills on biochemical methods.
Theoretical concepts provided by interactive sessions. Practical sessions for practical skills. Tutorial sessions to facilitate the self-learning process.
The evaluation considers two individual assessment tools and four group assessments: two written assay about the theorical component and four reports elaborated during laboratorial classes.
Final classification = (theorical component x 0,7) + (practical component x 0,3).
None of the components may have a mark below 10 under 20.
Students that had mark of 10 or more in the practical component will be exempted from that component in the final exam.
Interactive expositive sessions allow students to integrate the basic concepts and participate in their own learning process Practical sessions will promote knowledge application in a practical perspective, development of laboratorial skills, as well as analysis and synthesis competences, and will promote teamwork. Tutorial sessions allow the acquisition of strategies for an efficient self-learning, through search and analysis of issues related to theoretical concepts.
A., Norberto, M. F., Pamplona, M. T., Mira, L. & Meireles M. M., (2008). Guia do laboratório de química e bioquímica, 2ª ed, LIDEL, D.L, 203 pp
Rodwell, V.W., Bender, D. A., Botham, K. M., Kennely, P. J., & Weil, P. A. (2015). Harper's illustrated biochemistry (30th ed.). NY: McGraw-Hill.
(Available at https://archive.org/details/HARPERSILLUSTRATEDBIOCHEMISTRY30th)
Voet, D., Voet, J. G. & Pratt, C. W.(2013), Fundamentals of Biochemistry: Life at the Molecular Level, 4th ed. John Wiley & Sons, 1077 pp
Ahern, K.; Rajagopal, I.; Tan T. Biochemistry: Free For All. 2018. Oregon State University (available at https://open.umn.edu/opentextbooks/textbooks/866)
Online Resources
https://oli.cmu.edu/courses/biochemistry-open-free/
https://www.nature.com/scitable/ebooks/essentials-of-cell-biology-14749010/
