Maria Paula de Sousa Ferreira da Silva Marinho Pinto - ESA
Responsável
Learning outcomes of the curricular unit (knowledge, skills and competences to be developed by the students)
Knowledge of structure and function of biomolecules and metabolism.
Syllabus
Theoretical 1. Biomolecules: 1.1. Carbohydrates. 1.2. Proteins. 1.3. Lipids. 1.4. Vitamins. 2. Enzyme catalysis and enzyme regulation. 3. Nucleic acids and transfer of genetic information. 4. Main catabolic pathways 4.1. Introduction to energy metabolism in biological reactions. 4.2. Pathways of glucose oxidation. 4.3. Catabolism of triacylglycerols. 4.4. Protein catabolism. 5. Photosynthesis: 5.1. Photosystems and photophosphorylation. 5.2. The reductive pentose phosphate cycle. 5.3. C3, C4 and CAM plants. Laboratorial 1. Sample Preparation. 2. Spectroscopic methods for assay of proteins and nucleic acids. 3. Methods of separation. 4. Enzymatic Catalysis.
Demonstration of the syllabus coherence with the curricular unit's learning objectives
It is intended to give the principles of chemical processes occurring in the organism, starting with biological molecules, characterization and properties, and focusing next on basic processes for energy production and synthesis of macromolecules
Teaching methodologies (including evaluation)
Teaching Methodology: interactive expository sessions; laboratory classes to acquire practical skills, analyze and interpret results. Continuous assessment: Theoretical component (CT) - 2 written tests (T1 and T2), with mandatory registration in the LMS. Practical component (CP) -up to four group forms/reports. Final Classification = 0.70 (CT)+ 0.30 (CP), CT= average of T1 and T2, and CP = average of the forms/reports. To be exempt, attendance in laboratory classes is mandatory and none of the components can have a grade lower than 8/20. Exam: Written assay; Final Classification = 0.70 (CT)+ 0.30 (CP). Partial exemption from the exam, as long as the grade for CT or CP, respectively, was equal to or greater than 10. In case of failure to pass the UC, the student can maintain the grade for the practical or theoretical component for up to 1 academic year. If you do not wish to maintain these conditions, the student must inform the UC manager by email within 15 days after the start of classes.
Demonstration of the coherence between the teaching methodologies and the learning outcomes
The theoretical sessions aim to provide theoretical foundations relating to biological molecules and metabolism. In laboratory sessions, students will acquire skills in techniques applied to the analysis of biomolecules. The tutorial sessions aim to analyze scientific articles and case studies relevant to the unit.
Bibliography (Mandatory resources)
Bettelheim, F. A. & Landesberg, J. M.(2001), Laboratory experiments for organic and biochemistry, 4th ed. Harcourt, 299 pp. Bettelheim, F. A., Brown, W. H. & March, J.( 2001), Introduction to organic & biochemistry, 4th ed.Harcourt, 463 pp Campos, L. S. (2005), Entender a bioquímica, 4ª ed. Escolar Editora, 683 pp. Martinho Simões, J. A.,. Botas Castanho, M. A. R, Lampreia, I. M. S., Santos, F. J. V., Nieto de Castro, C. A., Norberto, M. F., Pamplona, M. T., Mira, L. & Meireles M. M., (2008). Guia do laboratório de química e bioquímica, 2ª ed, LIDEL, D.L, 203 pp Quintas, A.; Freire, A.P. & Halpern, M.J. (2008), Bioquímica - Organização Molecular da Vida, Lidel- Edicões Técnicas Lda, Lisboa, 758 pp Stryer, L.(1988), Biochemistry, 3rd ed., Freeman, N.Y, 1089 pp
